Ongoing projects

01- Sexual and Reproductive Health Observatory of Argentina

02- Carbetocin for the Treatment of Postpartum Haemorrhage: a Randomized Controlled Trial

03- Effect of folic acid supplementation in pregnancy on preeclampsia - Folic Acid Clinical Trial (FACT)

04- Misoprostol treatment for postpartum haemorrhage: To whom? Who will develop fever?

05- WHO Multicentre Study for the Development of Growth Standards from Fetal Life to Childhood: The Fetal Component.

06- Development of an International Guide to Monitor and Support Child Development

07- Effects of weight management interventions on maternal and fetal outcomes in pregnancy: Individual patient data (IPD) meta-analysis ......of randomized trials and model based economic evaluation.

08- Study on the process of patients with breast cancer from the suspected diagnosis until the end of treatment in the public health care system

09- Magic: a phase III, double blind, single center randomized placebo-controlled trial of topic isosorbide dinitrate for hemorrhoidal disease during the early postpartum period.

10- Building opportunities for regionalization as a strategy to enhance the capacity of the health system to respond to maternal and child care. The case of the province of Santa Fe

11- WHO recommendation Guidelines for Antenatal Care.

12- Simplified treatment for eclampsia prevention using magnesium sulfate (STEPMAG)

13- Maternal Mortality in Argentina: situation analysis of the underreport of maternal death of women from 10 to 49 years old in a sample population in Argentina.

Projects performed


CORONIS: International study of caesarean section surgical techniques: The follow-up study.


Screening for Preeclampsia: evaluation of the predictive ability of angiogenic factors for preeclampsia

Antenatal Care for healthy pregnant women: A mapping of interventions from existing guidelines to inform the development of new .WHO guidance on Antenatal Care.


A systematic review on early postnatal discharge from hospital for healthy mothers and term babies

Maternal and neonatal severe morbidity: observational study in the Provinces of Corrientes and Santa Fe in order to strengthen the monitoring on health services and guide the response capacity in the health care system

Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the WHO Multi-country Survey on Maternal


CORONIS Trial: International study of caesarean section surgical techniques.

Systematic review on Preeclampsia/ Eclampsia Incidence

Who Multicountry Survey on Maternal and Newborn Health (Latin-American, Africa and Asia)

Treatment of mild to moderate hypertension for the prevention of preeclampsia: a multicentre randomized clinical trial

Systematic review of the literature of birth spacing and outcomes using GRADE methodologies


Active management of the third stage of labour without controlled cord traction: a randomized non-inferiority controlled trial

E-based clinically integrated EBM course.

Update of the WHO guidelines for the prevention and management of postpartum haemorrhage.

Evaluation of Safe and Family Centered Maternity Hospitals Initiative

Interventions affecting cesarean rates: an overview of systematic reviews


Non-specific intravenous immunoglobulin therapy for suspected or proven neonatal sepsis: an international, placebo controlled, multicentre randomised trial (INIS)


Misoprostol to treat postpartum hemorrhage: a randomized controlled trial

The SUPPORT Collaboration (supporting Policy Relevant Reviews and Trials)

Effect of calcium supplementation to low calcium intake pregnant women on placental hemodynamic and fetal growth: a randomised clinical trial

Ecological Fallacy: empirical evaluation of different methods of analysis of aggregated data



A multicentre, double blind, placebo controlled, randomized trial to evaluate the effectiveness of a one-day versus 7-day regimen of nitrofurantoin for the treatment of asymptomatic bacteriuria in pregnancy

Evaluation of urine screening tests to detect asymptomatic bacteriuria in pregnancy: a WHO cross-sectional study

Application of a set of maternal and newborn indicators to monitor the implementation of the WHO Global Reproductive Health Strategy in Rosario, Argentina


Effectiveness of the implementation of guidelines and procedures for normal labour in the maternities of J.M. Cullen and J.B. Iturraspe hospitals from the city of Santa Fe, Province of Santa Fe, Argentina.

Epidemiology of postpartum hemorrhage: a systematic review


Study of the prevalence in asymptomatic carriers of the ß hemolityc streptococcus during pregnancy

Effectiveness of the implementation of guidelines and procedures for normal labour in the maternities of J.M. Cullen and J.B. Iturraspe hospitals from the city of Santa Fe, Province of Santa Fe, Argentina.

Evaluation of the comprehensive health programme of woman, Municipality of Rosario

WHO Multicentre Study for the Development of Growth Standards


The Calcium supplementation for the prevention of pre-eclampsia among low calcium intake women: A randomized controlled trial.

Magpie follow-up study in women and their babies
Effect of timing of cord clamping on postnatal hematocrit values and clinical values ib term infants and the clinical
PraCTiHC (Pragmatic Randomised Controlled Trials in Health Care).
RAMOS (Reproductive Age Mortality Survey)
WHO Global Survey for Maternal and Perinatal Health: cesarean delivery rates and pregnancy outcomes.


Adolescent Pregnancy: diagnosis for re-orientation of policies and health programmes
Systematic Review of etiology of preeclampsia


Long-term follow up of the International Randomized Term Breech Trial
Second opinion before a caesarean section
Systematic Review of the effectiveness of nutritional interventions for the prevention or treatment of child growth restriction


The Cost of Pregnancy in Rosario, Argentina: Economic evaluation. Within the Project: Randomised Controlled Trial for the Evaluation of a New Antenatal Care Model

Evaluation of the Impact and Costs of Health Programmes. A cross-sectional study


Quality of Prenatal Care: A neglected Reproductive Right for Women. Within the Project: Randomised Controlled Trial for the Evaluation of a New Antenatal Care Model

Magpie Trial Follow-up Study. A randomised clinical trial to evaluate the effectiveness of magnesium sulphate in the prevention of preeclampsia.
Survey on management of timing of the umbilical cord clamping after delivery in Maternity Hospitals of Argentina


ORACLE Trial. Overview of the Role of Antibiotics in Curtailing Labour and Early Delivery

Randomised control trial on the use of Misoprostol in the Management of Third Stage of Labour
The effect of high calcium exposure in uterus on the blood pressure during late childhood: long-term follow-up of a randomised controlled trial.

A Randomised Controlled Trial for the Evaluation of a New Antenatal Care Model


Randomised clinical trial on the approach to delivery in breech presentation at term


Nalbuphine vs Meperidine for analgesia during labor


Intra-umbilical vein injection and retained placenta: evidence from collaborative large randomised controlled trial.
Project to reduce child mortality in Argentina
Activities for the National Programme of Health Statistics


Long term effects of calcium supplementation during pregnancy


Activities of reinforcement of the National Program of Health Statistics of the National Ministry of Health and National Social Action (Part I and II)


Eclampsia trial


Is routine use of episiotomy justified?

Assessment of the quality of maternal-child health care in hospitals


Psychosocial support and pregnancy


Calcium supplementation during pregnancy for preventing hypertensive disorders
Secondary Data-Base Statistics Analysis

Randomized controlled study for the evaluation of a new prenatal control model.

Randomized controlled trial for the use of Misoprostol in the management of labor

WHO 2005 Global Survey on Maternal and Perinatal Health